Not that long ago, we celebrated the 30th anniversary of the first report of an AIDS-related illness. In June 1981, a short article in the Center for Disease Control’s weekly publication described five cases of Kaposi’s sarcoma, a rare cancer associated with immune deficiency and hitherto only seen with any consistency in some populations of Ashkenazi Jews. The cases described certainly didn’t fit the bill: these were young men, and no one could think of a good reason for them to develop Kaposi’s sarcoma.
There was a time before AIDS and HIV. It’s hard to imagine now, with almost weekly reminders of the dramatic pandemic which has unfolded over the last three decades. The numbers are staggering: according to the WHO, there are over 30 million people living with HIV, 2.5 million were infected in 2009 alone and, in the same year, 1.8 million died of the disease.
The other numbers which boggle the mind are those related to funding. There has been a rise from some $300 million spent on HIV/AIDS research in 1996 to nearly $16 billion in 2008. The scientific community has taken us from an utterly helpless situation, as it was in the early 1980s, to one where clinicians can choose from dozens of antiviral drugs, while vaccines and other preventative methods are continuously being investigated. It is hard to think of another situation in which so much progress has been made so quickly.
AIDS is now so much more than a scientific issue. It is a key part of many political, economical and developmental debates and is likely to remain so for decades to come.
However, it is worth remembering that the progress is not universal despite the efforts of the past thirty years. In Tanzania, witch-doctors advocate the rape of albino girls and the harvesting of their body parts for potions as a means of curing AIDS. Clearly, fear and hopelessness will push people to unbelievable extremes. So will ignorance: in the last few years we heard Thabo Mbeki, then President of South Africa, deny the link between HIV and AIDS, his successor, Jacob Zuma, claim he had showered after sex with an HIV-infected woman to protect himself from infection, and his health minister, Manto Tshabalala-Msimang, advocate beetroot, garlic and lemon concoctions to treat the disease.
We need no reminding that we remain a long way away from the end of the AIDS pandemic. The drugs we have are far from perfect, and the majority of HIV-infected people do not have access to them. The stigma associated with AIDS remains strong, both in developing countries and in the West. And all the while, HIV continues to evolve, keeping one step ahead of us and ruthlessly challenging scientists, clinicians and patients.